Senior Scientist - Molecular Biology and Antibody Engineering Team Leader:
Kyowa Kirin, Inc.- U.S.

Description
Kyowa Kirin is a fast growing global specialty pharmaceutical company that applies state-of-the-art biotechnologies to discover and deliver novel medicines in four areas of unmet need: oncology, nephrology, immunology and CNS/movement disorders. The North America organization includes three offices (in New Jersey and California) that focus on drug discovery, product development, and commercialization. Together, we work as a close-knit team to understand clinical needs and advance innovations that can have a profound impact on patient lives.

As a patient centric organization that strives to deliver innovative medicines to meet unmet needs, we feel that it is critical to follow the safety guidelines defined by CDC and OSHA. We believe the COVID-19 vaccine is the best way to manage COVID risk to you, your colleagues, your family and our society. With that in mind, we are taking the essential step to ensure the safety of our employees during this health crisis by requiring all US employees, temporary workers, agency employees and independent contractors to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. In accordance with applicable law, individuals may seek an accommodation for medical or disability-related conditions or sincerely held religious beliefs.

It is the policy of Kyowa Kirin North America, Inc. to provide equal employment opportunity to all qualified persons without regard to race, religion, creed, color, pregnancy, sex, age, national origin, disability, genetic trait or predisposition, veteran status, marital status, sexual orientation or affection preference or citizenship status or any other category protected by law.

Summary:

Kyowa Kirin, Inc., Research Division located in La Jolla, California is seeking a highly motivated Senior Scientist with demonstrated leadership, technical and analytical expertise in the area of antibody engineering, recombinant protein design, expression and production, and cell line generation to support the discovery of novel therapeutics for autoimmune and inflammatory diseases.

Essential Functions:

• Independently directs and executes molecular biology activities for multiple pipeline projects including design, generation, manipulation, and production of recombinant proteins, immunoglobulins and cell lines.
• Keeps up to date on advanced technologies for molecular biology and actively applies new concepts as appropriate to improve functional area capabilities.
• Maintains databases of proprietary generated reagents, e.g., vectors and cell lines.
• Develops short-term research plans for reagent generation based on needs and requests of the projects and Project Leaders.
• Establishes daily or weekly routines of the Molecular Biology Team members necessary to meet project timetables and project advancement.
• According to company's goals, participates in decision-making regarding drug discovery plans and short-term research strategies and priorities of the research field.
• Provides information to develop team or project-related budget for capital equipment, contract research, and critical supplies and conserves project related costs.
• Prepares necessary documentation for project reviews (proposals, monthly, quarterly, annual, or study reports), patent applications, publications, and/or animal, biosafety, or human subject protocols.
• May lead and manage at least one technology or pipeline project from idea through Lead Candidate selection.

Requirements:

Education

• Doctoral degree (Ph.D.) in molecular biology, biochemistry, biomolecular engineering, immunology, or related discipline.

Experience

• A minimum of 5 years Bio-Pharma industry experience in Molecular Biology and Antibody Engineering

Technical Skills

• Demonstrated knowledge of antibody optimization and humanization techniques through discovery of antibody-based biotherapeutics in an industry setting is required.
• Demonstrated team leadership is required.
• Strong understanding of protein structure-function relationships is preferred.
• Demonstrated knowledge of immunology is preferred.
• Experience in leading a pipeline project from idea to Lead Candidate Selection or championing a technology initiative is nice to have.

KKNA and all of its employees have an obligation to act in accordance with the law and with integrity in all our operations and interactions

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