Description
Our Culture: Why work with us?
At Foghorn Therapeutics, we believe in "People First, Mission Always."
We put "People First" because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics - demonstrated by our community speaking more than 22 languages and representing over 24 nationalities. We value our teammates as people, not just as employees - validated by our actions that let our people know that we care about them, their families, and their lives.
We say "Mission Always" because we know a relentless commitment to our mission will make a difference in the lives of others. We believe our success will come from evaluating the data to follow the science. We work hard to develop a new class of therapies that could improve the lives of over 2.5 million people with cancer.
Our culture is focused on succeeding through the evaluation of data, not people. And in that, relationships can flourish and develop.
Our Science:
The groundbreaking science behind our therapies continues to yield vital insights into diseases that have confounded physicians and researchers. Our core scientific approach is centered on the chromatin regulatory system, which opens and closes the right sections of DNA at the right time. Breakdowns in the chromatin regulatory system lead to a wide range of diseases, including cancer, impacting millions of people.
Our proprietary Gene Traffic Control® platform is a powerful tool for understanding and modulating the chromatin regulatory system. We are pursuing multiple treatments for breakdowns in this system. We are the only company with the ability to study and target the chromatin regulatory system at scale, in context, and in an integrated way.
The Role:
The Drug Discovery group at Foghorn is seeking an enthusiastic and self-motivated Scientist to design, develop and optimize cell-based assays and carry out in vitro screening to identify and characterize novel small molecule drug candidates.
The position requires extensive hands-on experience in cell-based assay development, including molecular and cellular biology techniques.
The candidate will have an immediate impact on our Gene Traffic Control® platform and pipeline.
In This Role, You'll Get To:
Actively contribute to the design and execution of in vitro cell-based assays including mechanism-informed assays, phenotypic and agnostic profiling methodologies such as Cell Painting
Be involved in the design and implementation of screening, target deconvolution, and hit triage strategies to deliver validated hits
Evaluate and implement emerging technologies and instrumentation enabling drug discovery
Identify and proactively troubleshoot technical issues, implement solutions under limited supervision
Maintain detailed records of experiment and effectively communicate findings to the project teams
Requirements
About you:
PhD + 0-2 yrs of experience or equivalent in Molecular/Cell Biology, Chemical Biology or related field
Extensive experience in cell culture and cell-based assays is required: proficiency in luminescence and fluorescence-based cell assays, immunofluorescence (HCI), and molecular biology techniques such as transfection, viral transduction, siRNA, Western blotting
Experience with high throughput screening and hit validation preferred
Excellent verbal and written communication skills and ability to collaborate effectively across functions
Well-organized with close attention to detail, critical analysis of data, good troubleshooting ability and a strong desire to make a difference
Benefits
Foghorn Therapeutics is pleased to provide you and your family with a comprehensive suite of benefits, including:
Highly competitive and inclusive medical, dental and vision coverage options
FSA and HSA for medical expenses and dependent care expenses
Free premium access to fitness, nutrition, and mindfulness classes
Unlimited paid time off policy
Discretionary winter shut down
Generous Paid Leave offerings, including 12 weeks of 100% paid parental leave
Paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
Free parking or subsidized commuter passes
Foghorn Therapeutics is a smoke-free, alcohol-free and drug-free work environment.
Foghorn is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Foghorn Therapeutics will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
