Scientist - Muscle Physiology:
Merck USA

Merck USA
South San Francisco California
Requisition ID: RES002031

Merck Research Laboratories South San Francisco, a wholly owned subsidiary of Merck and Co., is focused on driving discovery research.  Our new multi-disciplinary discovery research site offers state-of- the-art resources to explore the most promising science combined with Merck’s world-class R&D expertise in small molecules and biologics. Located within the heart of the Bay area’s biomedical community, research conducted in our new laboratories spans exploratory biology through early clinical development and is an integral part of Merck’s powerful world-class network of drug and vaccine discovery.
At Merck, we are inspired by the belief that a research-driven enterprise dedicated to scientific excellence can create medicines and vaccines that save and improve lives. Every employee is building on our proud legacy of scientific breakthrough. Our ability to impact the lives of patients worldwide depends on the integrity, creativity, humility and scientific acumen of our team. We are creating a diverse organization that is inspired by invention and founded on a culture of respect and collaboration. At Merck Research Labs South San Francisco, you’ll have the opportunity to expand your knowledge and skills through collaboration with talented and dedicated colleagues while advancing your career.

The Muscle Physiology therapeutic area within Discovery Research at Merck is seeking to recruit a Scientist that is highly motivated to applying their skills towards the identification and development of novel targets to treat a broad array of musculoskeletal diseases. The location will be the preclinical research laboratories at our new state of the art facility in the South San Francisco Bay Area. Beyond local connections, you will also be able to supplement your research activities by taking advantage of the technologies and capabilities of the wider Merck network of sites in Boston, MA as well as NJ and PA.


Responsibilities include and are not limited to the following:

  • Design, plan, execute, and troubleshoot biochemical, cell-based, and ex vivo experiments with minimal guidance.
  • Analyze data, interpret results, and identify anomalous findings.
  • Balance work on multiple projects in support of our drug discovery and development goals at various stages of the preclinical research phase from target validation through to lead optimization.
  • Provide scientific guidance and technical input into the Muscle Physiology and Cardiometabolic Disease portfolio.
  • Highly self-motivated, possess strong technical skills, have strong written and oral communication skills, and be able to work productively in a collaborative and cross functional team environment within and outside of the Merck Research Laboratories.





Education and Work Experience Requirement:

  • BS/BA in Biochemistry, Cell Biology, or Molecular Biology or related field with a minimum of (5) years Industry or Academic experience or a MS in Biochemistry, Cell Biology, or Molecular Biology or related field with a minimum of (2) years’ Industry or Academic experience

Required Experience:

  • Demonstrated ability to perform standard biochemical and enzymatic experiments.
  • Basic cell culture techniques.
  • Understanding of basic data graphing and biostatistics.

Preferred Experience:

  • Optimization and validation of in vitro enzymatic and/or cell-based assays.
  • Protein purification and characterization.
  • Ex vivo studies (e.g., muscle force generation, permeabilized myofibers, muscle bath).


The quality of our team is essential to our success. We are creating a new and innovative approach to rewarding our employees and establishing a comprehensive value proposition. Our competitive compensation program and benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and the people that matter the most in their lives. If you need an accommodation for the application process please email us at [email protected]
Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products.  Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for us all.

Job: Research Science
Other Locations:
Employee Status: Regular
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Company Trade Name: Merck
Basic Qualifications