Res Post Doc Fellow-Mitochondrial Unit of the Department of Anesthesiology and Critical Care:

Philadelphia Pennsylvania

LOC_COLKET-Colket Translational Research Req ID: 46841

Shift: Days

Employment Status: Regular - Full Time 

Job Summary

We have an exciting opportunity for a highly motivated postdoc scientist to join the Mitochondrial Unit of the Department of Anesthesiology and Critical Care at The Children’s Hospital of Philadelphia, Philadelphia, PA. Our team has developed a large animal model of traumatic brain injury (TBI) that allows us to directly assay clinically relevant brain dysfunction without the variability associated with human cohort studies. This project focuses on the development of novel biomarkers to predict TBI severity and secondary injury using liquid biopsies. The successful candidate will determine if cell-type-specific epigenetic mapping of cfDNA fragments can detect TBI with high sensitivity and specificity by performing the following key job responsibilities: process biological samples for multiple projects utilizing SOPs for developed NGS methods; analyze quality of library generation, troubleshoot challenges that occur during library preparation, and identify opportunities for protocol improvement; improve upon and/or develop new methods and protocols to address key experimental questions; work with supervisor to plan and meet project requirements and deadlines; and work collaboratively within the NGS team to complete team projects and achieve goals and deadlines.


The successful postdoctoral candidate will possess a BS or MS in biology or related field (required) and a minimum of 4 years of hands-on experience in and/or a minimum of 4 years of hands-on experience in an industry or academic research setting. The candidate will possess expertise in working with RNA, DNA, NGS library generation, and various NGS technologies. Preferred experience with automation and/or working with/analyzing NGS data. Strong communication, problem solving, and interpersonal skills preferred. Willing to work in both a team and independent setting. Ability to work in a dynamic environment and achieve deadlines while maintaining an organized workspace and laboratory notebook.

Job Responsibilities
  1. Conduct independent scholarly research and develop new methods and protocols
  2. Participate in project planning, recording and evaluation of data
  3. Acquire technical, lab management and grant writing skills
  4. Participate in seminars, lectures, poster sessions and presentation at national meetings
  5. Supervise junior lab members
  6. Assist with other research projects
Required Education and Experience
  • A terminal degree PhD, MD, DVM, etc.
  • According to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing
Preferred Education, Experience & Cert/Lic
Additional Technical Requirements

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer).

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

VEVRAA Federal Contractor/Seeking priority referrals for protected veterans.  Please contact our hiring official with any referrals or questions.

CHOP Careers Contact 

Talent Acquisition

2716 South Street, 6th Floor

Philadelphia, PA 19146 

Phone: 866-820-9288 

Email:[email protected]



Basic Qualifications