Postdoctoral Research Fellow - Drug Allergy and Hypersensitivity:
Merck USA

Merck USA
West Point Pennsylvania
Requisition ID: POS000277

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases. 

The Merck Research Laboratories (MRL) Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.

As a postdoctoral fellow in Molecular & Investigative Toxicology you will work with a highly collaborative and interdisciplinary team of scientists to apply understanding of fundamental mechanisms to solve drug development problems relating to drug hypersensitivity reactions. You will conceive, design, plan and implement a research program that will enable the creation of a preclinical testing strategy that can identify the immune mediated hypersensitivity potential of new drug candidates.

Responsibilities include but are not limited to:

  • Monitor, evaluate and leverage new technologies that enable preclinical de-risking of compounds.
  • Investigate mechanisms of immune related safety concerns raised in animal toxicology studies to help inform on relevance to humans. 
  • Lead the development and implementation of assays and protocols that enable de-risking of human safety findings that surface in human clinical trials and are not seen in conventional animal studies. 
  • Publish as primary or lead author in high quality, peer-reviewed, scientific journals 



Education Minimum Requirement: 

  • A PhD in pharmacology, toxicology or related life science field with less than (3) years of postdoctoral experience OR graduating with a PhD by summer of 2019. 
Required Experience and Skills: 

  • Experience with assay development and innovation 
  • Ability to design experiments, interpret and enable further development of a project 
  • Superior written and oral communication and interpersonal skills
  • Ability to work effectively in a team environment

Preferred Experience and Skills:

  • Demonstrated ability to publish in peer-reviewed journals
  • Expertise with any of the following: Analytical techniques: LCMS, Proteomics, ELISPOT, ELISA, flow cytometry, tissue culture 

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life. 


If you need assistance and/or a reasonable accommodation due to a disability during the application or the recruiting process, please send a request to [email protected].


Search Firm Representatives Please Read Carefully: 

Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity.  Please, no phone calls or emails.  All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck.  No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.


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Job: Post-Doctoral Fellow
Other Locations:
Employee Status: Regular
Number of Openings: 1
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Company Trade Name: Merck
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