Postdoctoral Research Fellow – Screening and Compound Profiling:
Merck USA

Merck USA
Kenilworth New Jersey
Requisition ID: POS000244

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases. 

Be a part of the legacy: MRL Postdoctoral Research Fellow Program
The Merck Research Laboratories (MRL) Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.

Position Overview:

As a postdoctoral fellow in the Department of Chemistry (Screening and Compound Profiling) you will work with a collaborative team of scientists to apply biochemical flux profiling to better understand the metabolic pathways that are altered in cancer and potentially identify new targets for cancer therapeutics.  This work requires a background in cancer biology and/or immunology, including an understanding of tumor/immuno-metabolism; studies will rely on stable isotope tracer methods and mass spectrometry-based readouts. Although this work will involve in vivo models, hands-on experience with in vitro (cell-based) models is desirable.

Responsibilities include but are not limited to:
  • Designing in vivo experimental plans and culturing cell / tissue systems.
  • Leading the development and implementation of mass spectrometry-based assays (primarily of small molecules).
  • Analyzing stable isotope kinetic data.

Education Minimum Requirement:  
  • PhD with less than 3 years of Postdoctoral Experience or achieved a Ph.D. by Spring/Summer of 2018. 
Required Experience and Skills:
  • Experience in immune-oncology and metabolic pathway biology.
  • Experience in cell and/or tissue culture methods.
  • Experience in GC and/or LC mass spectrometry.
Preferred Experience and Skills:
  • Knowledge of human physiology/concepts of metabolic regulation.
  • Ability to design experiments, interpret results, and utilize this information to enable assay development.
  • History of publication in peer-reviewed journals.
  • Working knowledge of metabolic flux profiling and metabolic engineering/mathematical modeling. 

Our employees are the key to our company’s success.  We demonstrate our commitment to our employees by offering a competitive and valuable rewards program.  Merck’s benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people that matter the most in their lives.
Merck is an equal opportunity employer, M/F/D/V – proudly embracing diversity in all of its manifestations. Former Military, Transitioning Service Members, National Guard & Reserves - We value your past and present service


Job: Post-Doctoral Fellow
Other Locations:
Employee Status: Regular
Number of Openings:
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Company Trade Name: Merck
Basic Qualifications