Postdoctoral Research Fellow – Immunology/Vaccines Modeling & Simulation:

Rahway New Jersey
Requisition ID: POS000229

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases. 

Be a part of the legacy: MRL Postdoctoral Research Fellow Program
The Merck Research Laboratories (MRL) Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.

Position Overview:

As a postdoctoral fellow in Merck Research Labs Pharmacometrics group based in Rahway, NJ, you will work with a highly collaborative team of scientists to apply logic-based dynamical network methods to analyze complex systems immunology studies – including microbiome profiling. This work will provide novel mechanistic understanding of vaccine hyporesponse in the elderly. 
Responsibilities include but are not limited to:
  • Assembling and exploring integrated clinical, cellular and molecular biology, and microbiome data 
  • Using modeling and simulation methods including logic-based dynamical network methods to identify systems immunology mechanisms that describe the data 
  • Developing or collaborating to develop new computational methods for causal analysis of complex profiling data 
  • Working with the research team to develop hypotheses for mechanisms underlying vaccine hyporesponse in the elderly, help design and analyze experiments 

Education Minimum Requirement:  
  • PhD with less than 3 years of Postdoctoral Experience or meet all requirements for a Ph.D. by Spring/early Summer of 2018 
Required Experience and Skills:
  • Experience in one or more of the following areas: immunology, infectious disease, microbiology 
  • Experience with data visualization, analysis and coding, using e.g. R and Matlab 
  • Experience with data modeling such as population pharmacokinetic models, chemical reaction kinetics-based models, or other model-based analyses 
Preferred Experience and Skills:
  • Experience with genomic data processing and mining, networking inference methods and mapping to molecular signaling pathways 
  • Familiarity with experimental methods of molecular and cellular biology; genetic, proteomic metabolomic and/or microbiome profiling 

Our employees are the key to our company’s success.  We demonstrate our commitment to our employees by offering a competitive and valuable rewards program.  Merck’s benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people that matter the most in their lives.
Merck is an equal opportunity employer, M/F/D/V – proudly embracing diversity in all of its manifestations. Former Military, Transitioning Service Members, National Guard & Reserves - We value your past and present service


Job: Post-Doctoral Fellow
Other Locations:
Employee Status: Regular
Number of Openings:
Shift (if applicable):
Hazardous Materials:
Company Trade Name: Merck
Basic Qualifications