Description
This 90-minute course will explain the importance of evaluating skin absorption of compounds from topically applied formulations for safety assessment, mechanistic studies and prior to conducting clinical studies.<br><br>
<b>Module 1:</b><br>
<li>Rationale for assessment of skin penetration</li>
<li>Regulatory parties involved:<br>
– OECD<br>
– CTFA<br>
– WHO</li>
<li>Description of general procedure</li><br><br>
<b>Module 2:</b><br>
<li>Preliminary required physical chemical properties</li>
<li>Types of diffusion cells</li>
<li>Finite and infinite dosing</li>
<li>Importance of vehicle applied</li>
<li>Fick’s first law for simple diffusion</li><br><br>
<b>Module 3:</b><br>
<li>Skin preparation:<br>
– Choice of skin<br>
– Species differences<br>
– Preparation of tissue samples:<br>
– Full thickness skin<br>
– Epidermal skin<br>
– Stratum corneum<br></li>
</li>Testing skin barrier integrity</li>
<li>Application of test compound</li>
<li>Receptor fluid</li>
<li>Evaluation of results</li>
<li>Summary</li>
01/01/0001
To
01/01/0001
Training Company
The Center for Professional Advancement (CfPA)
Industry
Pharmaceutical
Course Category
Address
AN ONLINE TRAINING FORMAT
AN ONLINE TRAINING FORMAT,
