Guidelines for Skin Absorption Studies Training Course :

<strong>Course Schedule - February 19-20, 2009</strong><br/><br/>In vitro skin absorption testing is part of recommended regulatory guidelines in the USA and used globallly to assess safety of exposure to chemicals when applied topically. The Personal Care Council (formally CTFA), the OECD (Organization for Economic Co-Operation and Development), WHO (World Health Organization) and SCCP (Scientific Committee of Consumer Products) - have all issued guidelines to address absorption of compounds from cosmetic formulations. The objective of these guidelines is to obtain quantitative and/or qualitative information on the amounts of chemicals that may penetrate the skin transdermally into the blood circulatory system during “real time” use.<br><br> Since in vitro studies have been demonstrated to provide reliable, reproducible data for topically applied formulations when the skin is the target of action, it is imperative that an understanding of penetration patterns be developed in order to allow for better product development as well as conservation of both resources and time in the process of product design.<br><br> This unique course will describe the importance of evaluating skin absorption of compounds from topically applied formulations. This description is an essential context for safety assessment, mechanistic studies and is fundamental to conducting clinical studies. It will also review key parameters in the guidelines and provide tools for further research.