Description
POSITION: Biology Research Associate
Would you like to discover next-generation medicines? At Rgenta Therapeutics, we unlock the therapeutic potentials of targets that are highly disease-relevant but undruggable by traditional protein-targeting approaches. We have built proprietary RNA-targeting platforms that leverage our deep knowledge and innovative ideas in data-driven genomics, computational biology, high-throughput screening, and medicinal chemistry. We are a vibrant and exciting venture-backed startup located in the Greater Boston area. Developing new medicines demands a team of individuals with scientific curiosity, a can-do attitude, passion for progress, complementary skills, and thinking outside the box. Join Rgenta to discover new medicines and make scientific breakthroughs!
ROLE RESPONSIBILITIES:- Design, develop, and optimize novel biochemistry and cell-based assays for lead discovery and optimization
- Develop and maintain state-of-the-art automation workflow for high-throughput screening and hit confirmation
- Design and execute molecular biology, cell biology, and genomics experiment to support target discovery and validation
- Responsible for screening data acquisition, tracking, and processing
BASIC QUALIFICATIONS:- MS degree in Biology or Pharmacology, or equivalent industrial experience
- Minimum 1-2 years of relevant research experience in the academic or pharmaceutical industry
- Broad experience with molecular and cell biology experimental techniques (e.g. tissue culture, RT-PCR, qPCR, Western, ELISA, siRNA, shRNA, CRISPR)
- Experience with cell based or biochemical assays is desirable
- Experience in developing plate-based HTS assays and automation workflow is desirable
- Experience with NGS-based genomic profiling techniques such as RNA-seq, ChIP-seq, Amplicon-seq is a plus
- Demonstrated learning agility and success moving into and mastering new or unfamiliar areas of science