Associate Scientist / Scientist I (Discovery Biology):
Neurona Therapeutics

1571396002
Neurona Therapeutics
South San Francisco California
Biotech
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Description

Associate Scientist / Scientist 1 (Discovery Biology)

Neurona Therapeutics is a clinical stage biotechnology company based in South San Francisco focused on the development of neuronal cell-based therapies for neurological disease. Our ideal candidate is a self-motivated individual who has a passion for scientific research. This is a fantastic opportunity for a junior scientist to join a team, work on transformative science, and take part in building an exciting, science-driven company and develop groundbreaking cell therapy products.

Responsibilities:

  • Collaborate in a team to develop next-generation cell products for the clinical pipeline.
  • Apply gene editing, viral gene delivery, and/or chemical screens to develop neuronal cell products with reduced immunogenicity, enhanced potency and/or accelerated maturation.
  • Develop cell-based assays to test and validate hypotheses.
  • Characterize cell products (immuno cyto-chemistry, Flow cytometry, RT-QPCR, RNA sequencing).
  • Conduct fluorescence- or magnetic -activated cell sorting experiments.
  • Maintain human pluripotent stem cells and differentiate into a variety of neuronal lineages utilizing scales from 384 well plates to regular and large-scale culture vessels.
  • Identify lead methods and conduct validation and scale up experiments. Collaborate with Process and Preclinical departments to support disease modifying activity studies in animal models.
  • Maintain detailed records, perform data analysis, and report results during team meetings

Required Qualifications:

  • PhD (+0-3 years of relevant experience) or Master's degree (+ 6-8 years of relevant experience) in cell and molecular biology (or a related field).
  • Hands on experience with human stem cell culture maintenance and in vitro differentiation.
  • Expertise in at least one area of: neuroimmunology/neuro inflammation, neurodevelopmental biology, or CRISPR screens
  • Proven scientific achievements by high publication records
  • Able to take initiative to improve work processes, develop innovative scientific methodologies and approaches to enhance research productivity.
  • High integrity, great organization and ability to multitask while working within fast-paced timelines
  • Critical thinking, strong team player and problem-solver
  • Excellent writing, verbal communication, and interpersonal skills
  • Willing to work a limited number of hours on some weekends.

Preferred Qualifications:

  • Knowledge in neuroscience and human developmental biology
  • Experience in cell assay development, immunohistochemistry, and flow cytometry analysis
  • Experience in high content microscopy/screening, CRISPR screens, calcium imaging or MEAs (multi-electrode arrays) is a plus.

For immediate consideration, please email your resume to: . Interested in learning more about our science and our team? Please visit our website at .

Neurona is proud to be an equal opportunity employer and will consider all qualified applicants for employment.