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Principal Scientist, Computational Chemistry
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Principal Scientist, Computational Chemistry : GlaxoSmithKline
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| Job Number |
60880 |
| Employee Type |
Full Time |
| Company Name |
GlaxoSmithKline |
| Location |
Research Triangle Park
North-Carolina
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| Salary (year) |
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| Experience |
2 to 5 Years |
| Start Date |
6/29/2010 |
| Industry |
Pharmaceutical |
| Job Type |
Science |
| Required Degree |
PhD |
| Relocation |
Not Required |
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| Description |
Basic Qualification
This position requires a Ph.D. (or equivalent) in Computational Chemistry, Chemistry, Biochemistry, Biophysics or related fields.
Details
The computational chemistry group at Research Triangle Park, a component of Computational and Structural Chemistry within Platform Technologies and Science, is seeking a scientist to apply the methods of computational chemistry to the discovery of new drugs. These methods may include molecular mechanics, quantum mechanics, molecular docking calculations, protein modelling, pharmacophore generation and analysis, virtual screening, ADME modelling, QSAR, statistics and general data integration and analysis. The candidate should have practical experience with several of these methodologies, or deeper expertise in one or more of these areas. The scientist may develop tools or methodology for these calculations or for the analysis and interpretation of their results. Experience with programming and/or scripting languages is an advantage. Using these techniques, the scientist will work closely with medicinal chemists and project teams to design compounds with improved potency, selectivity, functional behavior and/or ADME properties. Some knowledge of medicinal chemistry is an advantage. The candidate must have excellent communication skills, and must work effectively with scientists from other disciplines. |
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| Requirements |
Preferred Qualification
Any post-doctoral or industrial experience would be preferred. Excellent written and oral communication skills are essential. |
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